Bioactivity | PLpro/RBD-IN-1 (compound 5) is a dual SARS-CoV-2 PLpro and spike protein RBD inhibitor with IC50s of 7.197 μM and 8.673 μM, respectively[1]. |
Target | IC50: 7.197 μM (SARS-CoV-2 PLpro) and 8.673 μM (spike protein RBD) |
Name | PLpro/RBD-IN-1 |
CAS | 1282451-83-5 |
Formula | C13H10N4O |
Molar Mass | 238.24 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Mohammed Salah Ayoup, et al. Repurposing 1,2,4-oxadiazoles as SARS-CoV-2 PLpro inhibitors and investigation of their possible viral entry blockade potential. Eur J Med Chem. 2023 Apr 5;252:115272. |