| Bioactivity | PKR activator 5 (Compound 18) is an activator for pyruvate kinase R (PKR) with an AC50 of 28 nM[1]. |
| Target | AC50: 28 nM (PKR) |
| CAS | 2761226-35-9 |
| Formula | C23H19ClFN9O |
| Molar Mass | 491.91 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yu C, et al., The search for pyruvate kinase-R activators; from a HTS screening hit via an impurity to the discovery of a lead series. Bioorg Med Chem Lett. 2024 Jun 29;110:129865. |