PKN1/2-IN-1_product_DataBase

CAS: 942425-34-5 F: C14H15N3O W: 241.29

PKN1/2-IN-1 is a potent, cell penetrant and selective PKN2 (PRK2) inhibitor (IC50=16 nM; Ki=8 nM).

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity

PKN1/2-IN-1 is a potent, cell penetrant and selective PKN2 (PRK2) inhibitor (IC50=16 nM; Ki=8 nM)[1].

Target

IC50: 16 nM, Ki: 8 nM (PKN2) IC50: 108 nM, Ki: 210 nM (PKN1).

Name

PKN1/2-IN-1

CAS

942425-34-5

Formula

C14H15N3O

Molar Mass

241.29

Appearance

Solid

Transport

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Reference

[1]. Scott F, et al. Development of dihydropyrrolopyridinone-based PKN2/PRK2 chemical tools to enable drug discovery. Bioorg Med Chem Lett. 2022;60:128588.

PeptideDB

PKN1/2-IN-1

CAS: 942425-34-5 F: C14H15N3O W: 241.29