Bioactivity | PKA Regulatory Subunit II Substrate (RII phosphopeptide) is a tool peptide derived from the regulatory subunit Type II (RII) of cyclic AMP-dependent protein kinase (PKA). PKA Regulatory Subunit II Substrate is commonly used to mimic the phosphorylation of protein kinases and as a specific substrate for protein phosphatases to assess the activities of these enzymes[1]. |
CAS | 103659-06-9 |
Sequence | Asp-Leu-Asp-Val-Pro-Ile-Pro-Gly-Arg-Phe-Asp-Arg-Arg-Val-{pSer}-Val-Ala-Ala-Glu |
Shortening | DLDVPIPGRFDRRV-{pSer}-VAAE |
Formula | C92H151N28O32P |
Molar Mass | 2192.33 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Wang Lu, et al. "A novel peptide exerts potent immunosuppression by blocking the two-site interaction of NFAT with calcineurin." Journal of Biological Chemistry 295.9 (2020): 2760-2770. |