| Bioactivity | PIYLGGVFQ is a peptide inhibitor for TNF-α. PIYLGGVFQ inhibits TNF-α-mediated apoptosis, NF-κB nuclear translocation and activation. PIYLGGVFQ exhibits anti-arthritic activity in the CIA mouse model[1]. |
| Sequence | Pro-Ile-Tyr-Leu-Gly-Gly-Val-Phe-Gln |
| Shortening | PIYLGGVFQ |
| Formula | C49H72N10O12 |
| Molar Mass | 993.16 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sahu D, et al., Novel peptide inhibitor of human tumor necrosis factor-α has antiarthritic activity. Sci Rep. 2024 Jun 5;14(1):12935. |