| Bioactivity | PIPES (1,4-Piperazinediethanesulfonic acid) disodium is an important component of PIPES buffer agent used in biochemistry[1]. |
| Invitro | To prepare the pH PIPES buffer, 173 g of 1,4-piperazinediethanesulfonic acid are dissolved into 1 L of deionized water. The pH of the PIPES buffer is adjusted to 6.8 by adding pellets of sodium hydroxide.PIPES disodium can be used to PIPES buffer, it can prevent the glutaraldehyde fixation induced lipid loss and artifacts[1]. |
| Name | PIPES disodium |
| CAS | 76836-02-7 |
| Formula | C8H16N2Na2O6S2 |
| Molar Mass | 346.33 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
| Reference | [1]. Jason Moggridge, et al. Sensitive Detection of Immunoglobulin G Stability Using in Real-Time Isothermal Differential Scanning Fluorimetry: Determinants of Protein Stability for Antibody-Based Therapeutics. Technol Cancer Res Treat. 2017 Dec;16(6):997-1005. |
PIPES disodium
CAS: 76836-02-7 F: C8H16N2Na2O6S2 W: 346.33
PIPES (1,4-Piperazinediethanesulfonic acid) disodium is an important component of PIPES buffer agent used in biochemistr
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