| Bioactivity | PIP5K1C-IN-1 (Compound 30) is a potent PIP5K1C inhibitor, with an IC50 of 0.80 nM. PIP5K1C-IN-1 exhibits low total clearance in mice and high levels of kinase selectivity. PIP5K1C-IN-1 can be used for the research of cancer and chronic pain[1]. |
| Target | PIP5K1C |
| Formula | C20H20ClN5O |
| Molar Mass | 381.86 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ochiai K, et al. Discovery of Novel Bicyclic Pyrazoles as Potent PIP5K1C Inhibitors. ACS Medicinal Chemistry Letters, 2024. |