| Bioactivity | PI3Kδ/BET-IN-1 (compound 10b) shows excellent and balanced activities against PI3Kδ (IC50 = 112 nM) and BRD4-BD1 (IC50 = 19 nM) and exhibits strong antiproliferative activities in DLBCL cells[1]. |
| CAS | 3054869-10-9 |
| Formula | C27H34N6O3S |
| Molar Mass | 522.66 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kai Ran, et al. Design, Synthesis, and Biological Evaluation of Thieno[3,2-d]pyrimidine Derivatives as the First Bifunctional PI3Kδ Isoform Selective/Bromodomain and Extra-Terminal Inhibitors. J Med Chem. 2025 Jan 24. |
PI3Kδ/BET-IN-1
CAS: 3054869-10-9 F: C27H34N6O3S W: 522.66
PI3Kδ/BET-IN-1 (compound 10b) shows excellent and balanced activities against PI3Kδ (IC50 = 112 nM) and BRD4-BD1 (IC50
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.