| Bioactivity | PI3Kδ-IN-3 (Compound 11) is a PI3Kδ inhibitor (IC50: 9 nM). PI3Kδ-IN-3 inhibits B cell function. PI3Kδ-IN-3 has good pharmacokinetic properties[1]. |
| Target | 9 nM, 0.262 μM, 1.65 μM, 4.63 μM (PI3Kδ, PI3Kα, PI3Kβ, PI3Kγ) |
| Name | PI3Kδ-IN-3 |
| CAS | 1431540-99-6 |
| Formula | C28H24N6O3 |
| Molar Mass | 492.53 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hoegenauer K, et al. Discovery and Pharmacological Characterization of Novel Quinazoline-Based PI3K Delta-Selective Inhibitors. ACS Med Chem Lett. 2016 Jun 2;7(8):762-7. |