| Bioactivity | PI3Kα-IN-7 (Compound A12) is a potent PI3Kα inhibitor. PI3Kα-IN-7 also inhibits PI3Kβ. PI3Kα-IN-7 decreases cancer cells mitochondrial membrane potential and induces apoptosis[1]. |
| Invitro | PI3Kα-IN-7 (Compound A12) shows potent antitumor activities against HCT116, PC-3, MCF-7, A549 and MDA-MB-231 cell lines with IC50 values of 3.24 μM, 14.37 μM, 7.39 μM, 7.10 μM, and 16.85 μM, respectively[1]. |
| Name | PI3Kα-IN-7 |
| CAS | 2417098-53-2 |
| Formula | C17H22N8O2S |
| Molar Mass | 402.47 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
PI3Kα-IN-7
CAS: 2417098-53-2 F: C17H22N8O2S W: 402.47
PI3Kα-IN-7 (Compound A12) is a potent PI3Kα inhibitor. PI3Kα-IN-7 also inhibits PI3Kβ. PI3Kα-IN-7 decreases cancer
Data collection：peptidedb@qq.com
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