| Bioactivity | PI3K-IN-55 (Compound 6a) is a potent inhibitor for PI3K. PI3K-IN-55 affects PI3K/Akt/p53 signaling pathway, inhibits the proliferation of cancer cells A549, Hela, HepG2, MCF-7 and HT-29, with IC50s of 1.03-6.78 μM. PI3K-IN-55 induces apoptosis in cell MCF-7[1]. |
| Formula | C30H28N2O12S |
| Molar Mass | 640.61 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhou H, et al., In vitro anticancer study of novel curcumin derivatives via targeting PI3K/Akt/p53 signaling pathway. Mol Divers. 2024 Jul 1. |