| Bioactivity | PI3K-IN-18 (Compound 1) is a PI3K inhibitor, and can also effectively inhibit the homologous enzymemTOR. The IC50 values of PI3K-IN-18 for mTOR and PI3K-α were 49 nM and 41 nM, respectively[1]. |
| CAS | 371943-05-4 |
| Formula | C16H15N3O2S |
| Molar Mass | 313.37 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Verheijen, Jeroen C et al. “Discovery of 2-arylthieno[3,2-d]pyrimidines containing 8-oxa-3-azabi-cyclo[3.2.1]octane in the 4-position as potent inhibitors of mTOR with selectivity over PI3K.” Bioorganic & medicinal chemistry letters vol. 20,1 (2010): 375-9. |
PI3K-IN-18
CAS: 371943-05-4 F: C16H15N3O2S W: 313.37
PI3K-IN-18 (Compound 1) is a PI3K inhibitor, and can also effectively inhibit the homologous enzymemTOR. The IC50 values
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