| Bioactivity | PHF6 (VQIVYK) TFA is a self-assembly sequence capable of initiating the full-length tau protein aggregation. PHF6 TFA is mapped to the third microtubule-binding repeat region of the tau protein[1]. | ||||||
| Invitro | Aggregated tau-PHF6 (VQIVYK) TFA potentiates NLRP3 inflammasome expression and autophagy in human microglial cells[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> PHF6 TFA 相关抗体: | ||||||
| Sequence | Val-Gln-Ile-Val-Tyr-Lys | ||||||
| Shortening | VQIVYK | ||||||
| Formula | C36H60N8O9.xC2HF3O2 | ||||||
| Molar Mass | 748.91 (free base) | ||||||
| Appearance | 固体 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
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| Reference | [1]. Chinmaya Panda, et al. Aggregated Tau-PHF6 (VQIVYK) Potentiates NLRP3 Inflammasome Expression and Autophagy in Human Microglial Cells. Cell. 2021 Jun 30;10(7):1652. |
PHF6 TFA
CAS: F: C36H60N8O9.xC2HF3O2 W: 748.91 (free base)
PHF6 (VQIVYK) TFA is a self-assembly sequence capable of initiating the full-length tau protein aggregation. PHF6 TFA is
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