| Bioactivity | PGN-9856 is a selective and high affinity (pKi ≥ 8.3) ligand at EP2 receptor. PGN-9856 is a potetn and non-prostanoid EP2 receptor agonist (pEC50 ≥ 8.5). PGN-9856 shows anti-inflammatory and anti-glaucoma activities[1]. | |||||||||
| Name | PGN-9856 | |||||||||
| CAS | 863704-91-0 | |||||||||
| Formula | C21H15F2NO4 | |||||||||
| Molar Mass | 383.34 | |||||||||
| Appearance | 固体 | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
|
|||||||||
| Reference | [1]. Coleman RA, et al. The affinity, intrinsic activity and selectivity of a structurally novel EP2 receptor agonist at human prostanoid receptors. Br J Pharmacol. 2019 Mar;176(5):687-698. |