Bioactivity | PFI-7 is a probe, which binds to human GID4 (KD is 79 nM), and antagonizes the binding of Pro/N-degrons. PFI-7 can be utilized in C-terminal to LisH (CTLH) complex research and development of targeted protein degradation[1]. |
CAS | 2910938-58-6 |
Formula | C24H27N5O |
Molar Mass | 401.50 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Owens DDG, et al., A chemical probe to modulate human GID4 Pro/N-degron interactions. Nat Chem Biol. 2024 May 21. |