Bioactivity | PF-4778574 is a positive allosteric modulation of AMPA receptor with EC50 of 45 to 919 nM in differenct cells. |
Target | EC50: 45 to 919 nM (AMPAR) |
Name | PF-4778574 |
CAS | 1219633-99-4 |
Formula | C19H22N2O3S2 |
Molar Mass | 390.52 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Roberts BM, et al. Prevention of ketamine-induced working memory impairments by AMPA potentiators in a nonhuman primate model of cognitive dysfunction. Behav Brain Res. 2010 Sep 1;212(1):41-8. |