| Bioactivity | PF-07202954 is a weakly basic DGAT2 inhibitor with an IC50 of 10 nM for human DGAT2. PF-07202954 lowers liver triglyceride content in a Western-diet-fed rat model[1]. |
| Name | PF-07202954 |
| CAS | 2639372-47-5 |
| Formula | C22H23FN6O3 |
| Molar Mass | 438.45 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kevin J Filipski, et al. Design of Next-Generation DGAT2 Inhibitor PF-07202954 with Longer Predicted Half-Life. ACS Med Chem Lett. 2023 Oct 2;14(10):1427-1433. |
PF-07202954
CAS: 2639372-47-5 F: C22H23FN6O3 W: 438.45
PF-07202954 is a weakly basic DGAT2 inhibitor with an IC50 of 10 nM for human DGAT2. PF-07202954 lowers liver triglyceri
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