| Bioactivity | PF-06442609 is an orally active γ‑secretase modulator, with an IC50 of 6 nM for Aβ42. PF-06442609 possesses brain good penetration[1]. |
| CAS | 1402002-76-9 |
| Formula | C24H24F4N4O3 |
| Molar Mass | 492.47 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Martin Pettersson, et al. Design of Pyridopyrazine-1,6-dione γ-Secretase Modulators that Align Potency, MDR Efflux Ratio, and Metabolic Stability. ACS Med Chem Lett. 2015 Apr 3;6(5):596-601. |
PF-06442609
CAS: 1402002-76-9 F: C24H24F4N4O3 W: 492.47
PF-06442609 is an orally active γ‑secretase modulator, with an IC50 of 6 nM for Aβ42. PF-06442609 possesses brain goo
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