Bioactivity | PF-06380101 (Aur0101), an auristatin microtubule inhibitor, is a cytotoxic Dolastatin 10 analogue. PF-06380101 (Aur0101) shows excellent potencies in tumor cell proliferation assays and differential ADME properties when compared to other synthetic auristatin analogues that are used in the preparation of ADCs. | ||||||||||||
Name | PF-06380101 | ||||||||||||
CAS | 1436391-86-4 | ||||||||||||
Formula | C39H62N6O6S | ||||||||||||
Molar Mass | 743.01 | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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