| Bioactivity | PF-06284674 (PKM2 activator 1) (Compound 8) is a PKM2 activator that can be used in cancer research[1]. |
| Invitro | PF-06284674 (PKM2 activator 1) (Compound 8) 在 Huh7 细胞中激活 PKM2 (EC50 = 70 nM)，诱导 PKM2 四聚体的形成[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> PF-06284674 相关抗体: |
| CAS | 1434288-24-0 |
| Formula | C17H14N4O |
| Molar Mass | 290.32 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Guo C, et al. Discovery of 2-((1H-benzo [d] imidazol-1-yl) methyl)-4H-pyrido [1, 2-a] pyrimidin-4-ones as novel PKM2 activators[J]. Bioorganic & medicinal chemistry letters, 2013, 23(11): 3358-3363. |