| Bioactivity | PF-05387252 is a potent and selective IRAK4 inhibitor with the activity of inhibiting endogenous TLR signaling pathways. PF-05387252 has shown anti-inflammatory activity in experimental models and may have potential clinical application value in inhibiting psoriasis. Although PF-05387252 and its related compounds have shown anti-inflammatory effects in animal models, their efficacy in inhibiting psoriasis has not yet been verified[1]. |
| CAS | 1604034-71-0 |
| Formula | C25H27N5O2 |
| Molar Mass | 429.51 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Natural Modulators of Endosomal Toll-Like Receptor-Mediated Psoriatic Skin Inflammation |
PF-05387252
CAS: 1604034-71-0 F: C25H27N5O2 W: 429.51
PF-05387252 is a potent and selective IRAK4 inhibitor with the activity of inhibiting endogenous TLR signaling pathways.
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