Bioactivity | PF 02367982 is a potent and select progesterone receptor (PR) antagonist with an IC50 value of 47.3 nM. PF 02367982 has oral activity[1]. |
CAS | 913344-84-0 |
Formula | C19H20N4O2 |
Molar Mass | 336.39 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Alexander de Giorgio-Miller, et al. The translational pharmacology of a novel, potent, and selective nonsteroidal progesterone receptor antagonist, 2-[4-(4-cyano-phenoxy)-3,5-dicyclopropyl-1H-pyrazol-1-yl]-N-methylacetamide (PF-02367982). J Pharmacol Exp Ther. 2008 Oct;327(1):78-87. |