| Bioactivity | PF-00489791 (PF-489791) is a potent inhibitor of phosphodiesterase 5A with IC50 of 1.5 nM. PF-00489791 can enhance the relaxation of blood vessels within the kidney and so reduce blood pressure, improving renal function[1]. |
| Name | PF-00489791 |
| CAS | 853003-48-2 |
| Formula | C20H28N8O4S |
| Molar Mass | 476.55 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Frank S Menniti, et al. A non-brain penetrant PDE5A inhibitor improves functional recovery after stroke in rats. Restor Neurol Neurosci. 2012;30(4):283-9. |
PF-00489791
CAS: 853003-48-2 F: C20H28N8O4S W: 476.55
PF-00489791 (PF-489791) is a potent inhibitor of phosphodiesterase 5A with IC50 of 1.5 nM. PF-00489791 can enhance the r
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