| Bioactivity | PDI-IN-3 (compound 16F16) is a protein disulfide isomerase (PDI) inhibitor. PDI-IN-3 inhibits cell viability[1]. |
| Invitro | PDI-IN-3 (compound 16F16) (0.1, 1, 10, 100 µM; 48 h) 抑制 htt-Q25 和 htt-Q103 细胞的活力[1]。PDI-IN-3 (1, 2, 3, 4, 10 µM) 抑制 htt-N90Q73 诱导的脑切片 MSN (中棘神经元) 毒性[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> PDI-IN-3 相关抗体: Cell Viability Assay[1] Cell Line: |
| CAS | 922507-80-0 |
| Formula | C16H17ClN2O3 |
| Molar Mass | 320.77 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hoffstrom BG, et al. Inhibitors of protein disulfide isomerase suppress apoptosis induced by misfolded proteins. Nat Chem Biol. 2010 Dec;6(12):900-6. |