| Bioactivity | PDGFR Y1021 peptide (phosphorylation) is the phosphorylated fragment of platelet-derived growth factor receptor (PDGFR). PDGFR Y1021 peptide (phosphorylation) supports association of PLCγ to PDGFR through PLCγSH2 domains, and thus promotes the production of inositol phosphates and mitogenic response[1]. |
| CAS | 147428-10-2 |
| Sequence | Asp-Asn-Asp-{pTyr}-Ile-Ile-Pro-Leu-Pro-Asp-Pro-Lys |
| Shortening | DND-{pTyr}-IIPLPDPK |
| Formula | C64H99N14O24P |
| Molar Mass | 1479.52 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Valius M, et al., Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively. Mol Cell Biol. 1993 Jan;13(1):133-43. |