PeptideDB

PDGFR Y1021 peptide (phosphorylation)

CAS: 147428-10-2 F: C64H99N14O24P W: 1479.52

PDGFR Y1021 peptide (phosphorylation) is the phosphorylated fragment of platelet-derived growth factor receptor (PDGFR).
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Bioactivity PDGFR Y1021 peptide (phosphorylation) is the phosphorylated fragment of platelet-derived growth factor receptor (PDGFR). PDGFR Y1021 peptide (phosphorylation) supports association of PLCγ to PDGFR through PLCγSH2 domains, and thus promotes the production of inositol phosphates and mitogenic response[1].
CAS 147428-10-2
Sequence Asp-Asn-Asp-{pTyr}-Ile-Ile-Pro-Leu-Pro-Asp-Pro-Lys
Shortening DND-{pTyr}-IIPLPDPK
Formula C64H99N14O24P
Molar Mass 1479.52
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Valius M, et al., Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively. Mol Cell Biol. 1993 Jan;13(1):133-43.