| Bioactivity | PDGFR Y1021 peptide (non-phosphorylation) is the non-phosphorylated fragment of platelet-derived growth factor receptor (PDGFR). PDGFR Y1021 peptide (non-phosphorylation) blocks the PLCγ association to PDGFR through PLCγSH2 domain, and thus inhibits mitogenic response[1]. |
| CAS | 205173-94-0 |
| Sequence | Asp-Asn-Asp-Tyr-Ile-Ile-Pro-Leu-Pro-Asp-Pro-Lys |
| Shortening | DNDYIIPLPDPK |
| Formula | C64H98N14O21 |
| Molar Mass | 1399.54 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Valius M, et al., Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively. Mol Cell Biol. 1993 Jan;13(1):133-43. |
PDGFR Y1021 peptide (non-phosphorylation)
CAS: 205173-94-0 F: C64H98N14O21 W: 1399.54
PDGFR Y1021 peptide (non-phosphorylation) is the non-phosphorylated fragment of platelet-derived growth factor receptor
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