| Bioactivity | PDE5/HDAC-IN-1 (Compound 26) is a potent phosphodiesterase 5 (PDE5) and HDAC inhibitor with IC50 values of 46.3 nM and 14.5 nM, respectively. PDE5/HDAC-IN-1 induces cell apoptosis and shows anticancer activities[1]. |
| Invitro | PDE5/HDAC-IN-1 (Compound 26) shows growth inhibition with IC50 values of 12.35, 7.19 and 11.79 µM against HT-29, HCT-116 and SW-620 cells, respectively[1].PDE5/HDAC-IN-1 shows cytotoxic activity with IC50 values of 1.9, 1.5, 2.5, 5.5, 9.8, 18.6, 2 and 28.2 μM against Molt 4, Sup-T1, K562, AGS, PC-3, LNCaP, T47D and CCD966SK, respectively[1]. |
| Name | PDE5/HDAC-IN-1 |
| CAS | 2414921-48-3 |
| Formula | C27H29BrN4O4 |
| Molar Mass | 553.45 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
PDE5/HDAC-IN-1
CAS: 2414921-48-3 F: C27H29BrN4O4 W: 553.45
PDE5/HDAC-IN-1 (Compound 26) is a potent phosphodiesterase 5 (PDE5) and HDAC inhibitor with IC50 values of 46.3 nM and 1
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.