| Bioactivity | PDE5-IN-7 (compound 8) is a selective phosphodiesterase 5 (PDE 5) inhibitor with an IC50 value of 5 nM, while an IC50 of 300 nM for PDE 1[1]. | ||||||||||||
| Invitro | PDE5-IN-7 (compound 15, Desild) can be detected and isolated from Sildenafil (HY-15025) derivatives[2]. | ||||||||||||
| Name | PDE5-IN-7 | ||||||||||||
| CAS | 139756-21-1 | ||||||||||||
| Formula | C17H20N4O2 | ||||||||||||
| Molar Mass | 312.37 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Haning H, et al. Imidazo[5,1-f]triazin-4(3H)-ones, a new class of potent PDE 5 inhibitors. Bioorg Med Chem Lett. 2002 Mar 25;12(6):865-8. [2]. Assemat G, et al. Isolation and identification of ten new sildenafil derivatives in an alleged herbal supplement for sexual enhancement. J Pharm Biomed Anal. 2020 Nov 30;191:113482. |
PDE5-IN-7
CAS: 139756-21-1 F: C17H20N4O2 W: 312.37
PDE5-IN-7 (compound 8) is a selective phosphodiesterase 5 (PDE 5) inhibitor with an IC50 value of 5 nM, while an IC50 of
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