| Bioactivity | PDE5-IN-42 (Compound 42) is a potent and orally active PDE5 inhibitor with an IC50 of 0.04 nM. PDE5-IN-42 maintains selectivity over PDE6 and PDE11[1]. |
| Target | IC50: 0.04 nM (PDE5) |
| Name | PDE5-IN-42 |
| CAS | 936449-28-4 |
| Formula | C23H31N7O3 |
| Molar Mass | 453.54 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Tollefson MB, et al. 1-(2-Ethoxyethyl)-1H-pyrazolo[4,3-d]pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitors. Bioorg Med Chem Lett. 2010 May 15;20(10):3120-4. |
PDE5-IN-42
CAS: 936449-28-4 F: C23H31N7O3 W: 453.54
PDE5-IN-42 (Compound 42) is a potent and orally active PDE5 inhibitor with an IC50 of 0.04 nM. PDE5-IN-42 maintains sele
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