| Bioactivity | PDE5-IN-12 (compound 4h) is a potent phosphodiesterase-5 (PDE-5) inhibitor with an IC50 of 22 nM. PDE5-IN-12 shows anti-proliferative effects against the aortic cell line[1]. |
| Formula | C19H14ClFN4O3 |
| Molar Mass | 400.79 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zeinab S Abd-Rabo, et al. Design, synthesis, and biological evaluation of some new 2-phenyl-3,6-pyridazinedione derivatives as PDE-5 inhibitors. Bioorg Chem. 2024 Feb 16:145:107213. |