| Bioactivity | PDE4-IN-25 (compound 12) is a potent inhibitor of PDE4，with the IC50 of 0.1 μM. PDE4-IN-25 plays an important role in inflammatory diseases research[1]. |
| CAS | 346440-86-6 |
| Formula | C14H15N3O4 |
| Molar Mass | 289.29 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Icos Corp. Preparation of pyrazoles as cAMP-specific phosphodiesterase inhibitors for pharmaceutical use as anti-inflammatory agents. World Intellectual Property Organization, WO2001046172 A1 2001-06-28. |