| Bioactivity | PDD00017272 (34f) is a potent inhibitor of Poly(ADP-ribose) Glycohydrolase (PARG), with EC50 of 4.8 nM and 9.2 nM in biochemical assay and cell POM, respectively[1]. | ||||||||||||
| Name | PDD00017272 | ||||||||||||
| CAS | 1945950-20-8 | ||||||||||||
| Formula | C23H25N5O4S3 | ||||||||||||
| Molar Mass | 531.67 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Bohdan Waszkowycz, et al. Cell-Active Small Molecule Inhibitors of the DNA-Damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG): Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides. J Med Chem. 2018 Dec 13;61(23):10767-10792. |
PDD00017272
CAS: 1945950-20-8 F: C23H25N5O4S3 W: 531.67
PDD00017272 (34f) is a potent inhibitor of Poly(ADP-ribose) Glycohydrolase (PARG), with EC50 of 4.8 nM and 9.2 nM in bio
Data collection：peptidedb@qq.com
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