| Bioactivity | PD159790 is a selective endothelin-converting enzyme-1 (ECE-1) inhibitor, with an EC50 of 28.1 μM[1][2][3]. |
| Invitro | PD159790 (30 μM, pH = 6.9) 抑制 ECE 活性[2]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> PD159790 相关抗体: |
| CAS | 179598-53-9 |
| Formula | C16H18F3IN4 |
| Molar Mass | 450.24 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Janet Maguire, et al. Alternative pathway to endothelin-converting enzyme for the synthesis of endothelin in human blood vessels. J Cardiovasc Pharmacol. 2004 Nov:44 Suppl 1:S27-9. [2]. F D Russell, et al. Evidence for intracellular endothelin-converting enzyme-2 expression in cultured human vascular endothelial cells. Circ Res. 1999 Apr 30;84(8):891-6. [3]. K Ahn, et al. Novel selective quinazoline inhibitors of endothelin converting enzyme-1. Biochem Biophys Res Commun. 1998 Feb 4;243(1):184-90. |