| Bioactivity | PD1-PDL1-IN 1 (compound 16) is a potent programmed cell death 1 (PD-1) inhibitor. PD1-PDL1-IN 1 is useful as immune modulator[1]. |
| Invitro | PD-1 (or Programmed Cell Death 1 or PDCD1) is a ~55kD type I membrane glycoprotein and is a receptor of the CD28 superfamily that negatively regulates T cell antigen receptor signalling by interacting with the specific ligands. PD-1 is suggested to play significant role in the maintenance of self-tolerance[1]. |
| Name | PD1-PDL1-IN 1 |
| CAS | 2005454-12-4 |
| Formula | C14H23N7O6 |
| Molar Mass | 385.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Pottayil Govindan Nair Sasikumar , et al. 3-substituted-1,2,4-oxadiazole and thiadiazole compounds as immunomodulators. WO2016142886A2. |
PD1-PDL1-IN 1
CAS: 2005454-12-4 F: C14H23N7O6 W: 385.38
PD1-PDL1-IN 1 (compound 16) is a potent programmed cell death 1 (PD-1) inhibitor. PD1-PDL1-IN 1 is useful as immune modu
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