| Bioactivity | PD1-PDL1-IN 1 TFA (compound 16) is a potent programmed cell death 1 (PD-1) inhibitor. PD1-PDL1-IN 1 TFA is useful as immune modulator[1]. |
| Invitro | PD-1 (或程序性细胞死亡 1 或 PDCD1) 是一种 ~55kD I 型膜糖蛋白，是 CD28 超家族的受体，通过与特定配体相互作用负调节 T 细胞抗原受体信号。PD-1 被认为在维持自身耐受中发挥重要作用[1]。 |
| Name | PD1-PDL1-IN 1 TFA |
| Formula | C16H24F3N7O8 |
| Molar Mass | 499.40 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -20°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
| Reference | [1]. Pottayil Govindan Nair Sasikumar , et al. 3-substituted-1,2,4-oxadiazole and thiadiazole compounds as immunomodulators. WO2016142886A2. |
PD1-PDL1-IN 1 TFA
CAS: F: C16H24F3N7O8 W: 499.40
PD1-PDL1-IN 1 TFA (compound 16) is a potent programmed cell death 1 (PD-1) inhibitor. PD1-PDL1-IN 1 TFA is useful as imm
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