| Bioactivity | PD-89211 is a selective dopamine D4 receptor antagonist with a Ki value of 3.7 nM. PD-89211 reverses Quinpirole (HY-B1752A)-induced [3H]thymidine uptake in CHOpro5 cells (IC50 = 2.1 nM). PD-89211 regulates dopamine/norepinephrine metabolism in the hippocampus and can be used for research on central nervous system disorders such as schizophrenia[1]. |
| CAS | 444725-49-9 |
| Formula | C19H21ClN4O |
| Molar Mass | 356.85 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Pugsley TA, et al. The discovery of PD 89211 and related compounds: selective dopamine D4 receptor antagonists. Prog Neuropsychopharmacol Biol Psychiatry. 2002 Feb;26(2):219-26. |
PD-89211
CAS: 444725-49-9 F: C19H21ClN4O W: 356.85
PD-89211 is a selective dopamine D4 receptor antagonist with a Ki value of 3.7 nM. PD-89211 reverses Quinpirole (HY-B175
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