PD 404182 (Standard)

CAS: 72596-74-8 F: C11H11N3S W: 217.29

Paris saponin VII (Standard) is the analytical standard of Paris saponin VII. This product is intended for research and

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Bioactivity	Paris saponin VII (Standard) is the analytical standard of Paris saponin VII. This product is intended for research and analytical applications. Paris saponin VII (Chonglou Saponin VII) is a steroidal saponin isolated from the roots and rhizomes of Trillium tschonoskii. Paris saponin VII-induced apoptosis in K562/ADR cells is associated with Akt/MAPK and the inhibition of P-gp. Paris saponin VII attenuates mitochondrial membrane potential, increases the expression of apoptosis-related proteins, such as Bax and cytochrome c, and decreases the protein expression levels of Bcl-2, caspase-9, caspase-3, PARP-1, and p-Akt. Paris saponin VII induces a robust autophagy in K562/ADR cells and provides a biochemical basis in the treatment of leukemia.
CAS	72596-74-8
Formula	C11H11N3S
Molar Mass	217.29
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

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