| Bioactivity | PD-159020 is a non-selective ETA/ETB antagonist, with IC50s of 30 and 50 nM for hETA and hETB, respectively. |
| Target | IC50: 30 nM (hETA), 50 nM (hETB) |
| Invitro | PD-159020 demonstrates excellent inhibition of arachidonic acid release, AAR-B, with an IC50 of 0.23 μM. |
| Name | PD-159020 |
| CAS | 177904-00-6 |
| Formula | C32H25NO8 |
| Molar Mass | 551.54 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Amy Mbunker, et al. 1,3-diaryl-2-carboxyindoles as potent non-peptide endothelin antagonists. Bioorganic & Medicinal Chemistry Letters. Volume 6, Issue 9, 7 May 1996, Pages 1061-1066 |