Bioactivity | PD 118440 is an orally active dopamine (DA) agonist. PD 118440 has significant central nervous system effects, including inhibition of striatal DA synthesis, suppression of DA neuron firing, and reversal of Reserpine (HY-N0480)-induced depression in rats[1]. |
CAS | 108351-90-2 |
Formula | C11H17N3S |
Molar Mass | 223.34 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Jaen J C, et al. 4-(1, 2, 5, 6-Tetrahydro-1-alkyl-3-pyridinyl)-2-thiazolamines: a novel class of compounds with central dopamine agonist properties[J]. Journal of medicinal chemistry, 1990, 33(1): 311-317. |