| Bioactivity | PD 116152 is a phenazine Antibiotic with antimicrobial and antitumor activity. PD 116152 possesses cytotoxic activity against L1210 lymphocytic leukemia and human colon adenocarcinoma (HCT-8) cells with IC50 values of 5.2 x 10-7 M and 7.1 x 10-7 M, respectively. PD 116152 is promising for research of P388 lymphocytic leukemia[1]. |
| CAS | 101708-64-9 |
| Formula | C16H12N2O6 |
| Molar Mass | 328.28 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Smitka TA, et al. PD 116,152, a new phenazine antitumor antibiotic. Structure and antitumor activity. J Antibiot (Tokyo). 1986 Jun;39(6):800-3. [2]. Tunac J B, et al. PD 116, 152, a novel phenazine antitumor antibiotic discovery, fermentation, culture characterization and biological activity[J]. The Journal of Antibiotics, 1986, 39(2): 192-197. |
PD 116152
CAS: 101708-64-9 F: C16H12N2O6 W: 328.28
PD 116152 is a phenazine Antibiotic with antimicrobial and antitumor activity. PD 116152 possesses cytotoxic activity ag
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