Bioactivity | PD-1/PD-L1-IN 5 is a PD-1/PD-L1 protein/protein interaction inhibitor extracted from patent WO2017222976A1, compound Example 1, has an IC50 of ≤100 nM[1]. |
Target | IC50: ≤100 nM (PD-1/PD-L1) |
Invitro | The compounds modulate PD-1/PD-L1 protein/protein interaction and are useful in the treatment of various diseases including infectious diseases and cancer. The compounds can be used as immunomodulators[1]. |
Name | PD-1/PD-L1-IN 5 |
CAS | 2170209-51-3 |
Formula | C22H18N4O3S |
Molar Mass | 418.47 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Kaijiong Xiao, et al. Heterocyclic compounds as immunomodulators. WO2017222976A1. |