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PD-1/PD-L1-IN 5

CAS: 2170209-51-3 F: C22H18N4O3S W: 418.47

PD-1/PD-L1-IN 5 is a PD-1/PD-L1 protein/protein interaction inhibitor extracted from patent WO2017222976A1, compound Exa
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Bioactivity PD-1/PD-L1-IN 5 is a PD-1/PD-L1 protein/protein interaction inhibitor extracted from patent WO2017222976A1, compound Example 1, has an IC50 of ≤100 nM[1].
Target IC50: ≤100 nM (PD-1/PD-L1)
Invitro The compounds modulate PD-1/PD-L1 protein/protein interaction and are useful in the treatment of various diseases including infectious diseases and cancer. The compounds can be used as immunomodulators[1].
Name PD-1/PD-L1-IN 5
CAS 2170209-51-3
Formula C22H18N4O3S
Molar Mass 418.47
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Kaijiong Xiao, et al. Heterocyclic compounds as immunomodulators. WO2017222976A1.