| Bioactivity | PD-1/PD-L1-IN-42 (Compound B8.4) is an inhibitor of the interaction between PD-1 and PD-L1, with an EC50 of 0.1 μM. PD-1/PD-L1-IN-42 can be used for the research of cancer immunotherapy[1]. |
| Target | EC50: 0.1 μM (PD-1/PD-L1). |
| Sequence | Tyr-Arg-Cys-Met-Ile-Ser-Tyr-Gly-Gly-Ala-Asp-Tyr-Lys-Arg |
| Shortening | TRSPICYQIIDYKFN |
| Formula | C85H129N21O24S |
| Molar Mass | 1861.13 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Tseng TS, et al. Structure-Guided Discovery of PD-1/PD-L1 Interaction Inhibitors: Peptide Design, Screening, and Optimization via Computation-Aided Phage Display Engineering. J Chem Inf Model. 2024;64(5):1615-1627. |