Bioactivity | PD-1/PD-L1-IN-20 (Example 21) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-20 blocks PD-1/PD-L1 with the IC50 of 5.29 nM. PD-1/PD-L1-IN-20 can be used for the research of cancers, infectious diseases and autoimmune diseases[1]. |
Name | PD-1/PD-L1-IN-20 |
CAS | 2159138-01-7 |
Formula | C30H26BrClN2O3 |
Molar Mass | 577.90 |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Benzyl phenyl ether derivative, preparation method therefor, and pharmaceutical composition and uses thereof. WO2017202273A1. |