Bioactivity | PCSK9-IN-20 (Compound 3i) is a PCSK9 inhibitor with an IC50 of 3.96 µM. PCSK9-IN-20 decreases PCSK9 and increases LDLR protein expression in vitro[1]. |
Target | IC50: 3.96 µM (PCSK9) |
Name | PCSK9-IN-20 |
CAS | 2929219-77-0 |
Formula | C27H32N6O5S2 |
Molar Mass | 584.71 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Zhixin Ma, et al. Identification of benzothiazoles as novel PCSK9 inhibitors. Bioorg Med Chem Lett. 2023 Nov 6:129542. |