| Bioactivity | PCAF-IN-2 (compound 17) is a potent PCAF inhibitor with an IC50 value of 5.31 µM. PCAF-IN-2 shows anti-tumour activity. CAF-IN-2 induces apoptosis and arrest the cell cycle at the G2/M phase[1]. | ||||||||||||
| Invitro | PCAF-IN-2 shows anti-tumour activity with IC50s of 3.06, 5.69, 7.56, 2.83 µM for HePG2, MCF-7, PC3, HCT-116 cells, respectively[1].PCAF-IN-2 (10 µM; 24 h) induces apoptosis and arrest the cell cycle at the G2/M phase in HePG2 cells[1]. | ||||||||||||
| Name | PCAF-IN-2 | ||||||||||||
| CAS | 56173-05-8 | ||||||||||||
| Formula | C10H7F3N6 | ||||||||||||
| Molar Mass | 268.20 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
|