| Bioactivity | PBX-7011 TFA is a derivative of camptothecin (HY-16560), which inhibits expressions of the cancer related survival genes DDX5, Survivin, Mcl-1 and XIAP in cells FaDu, degrades DDX5 proteins and exhibits anticancer activity[1]. |
| Formula | C26H22F3N3O8 |
| Molar Mass | 561.46 |
| Appearance | 固体 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -20°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
| Reference | [1]. Jung DY, et al. Camptothecin derivatives that bind to ddx5 protein and prodrugs thereof. WO2023204631A1. 2023-10-26. |