| Bioactivity | PBOX-15 is a microtubule targeting agent. PBOX-15 induces apoptosis by promoting tubulin depolymerization in tumor cells[1]. |
| CAS | 354759-10-7 |
| Formula | C28H19NO3 |
| Molar Mass | 417.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Maginn EN, et al. PBOX-15, a novel microtubule targeting agent, induces apoptosis, upregulates death receptors, and potentiates TRAIL-mediated apoptosis in multiple myeloma cells. Br J Cancer. 2011 Jan 18;104(2):281-9. [2]. Mulligan JM, et al. Identification of tubulin as the molecular target of proapoptotic pyrrolo-1,5-benzoxazepines. Mol Pharmacol. 2006 Jul;70(1):60-70. |