| Bioactivity | PB200 is an HDAC6 inhibitor with an IC50 value of 1.97 nM. PB200 demonstrates significant antidepressant effects by restoring abnormal HDAC6 expression levels and alleviating neuroinflammation[1]. |
| Formula | C17H18FN3O2 |
| Molar Mass | 315.34 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhong X, et al. PET Imaging Assist Investigation of HDAC6 Expression Change in MDD and Evaluating Antidepressant Efficacy of a Newly Developed HDAC6 Inhibitor[J]. European Journal of Medicinal Chemistry, 2024: 116908. |