| Bioactivity | PARP10-IN-2 is a potent mono‐ADP‐ribosyltransferase PARP10 inhibitor with an IC50 of 3.64 μM for human PARP10. PARP10-IN-2 reveals potent inhibition on PARP2 and PARP15 with IC50s of 27 μM and 11 μM for human PARP2 and human PARP15, respectively[1]. |
| Invitro | PARP10-IN-2 (化合物 10) 在 HeLa-PARP10 细胞中通过克隆形成测定 (CFA) 的 IC50 为 1-2 μM[1]。 |
| Name | PARP10-IN-2 |
| CAS | 1042780-52-8 |
| Formula | C14H10N2O2 |
| Molar Mass | 238.24 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Patricia Korn, et al. Evaluation of 3- and 4-Phenoxybenzamides as Selective Inhibitors of the Mono-ADP-Ribosyltransferase PARP10. ChemistryOpen. 2021 Oct;10(10):939-948. |
PARP10-IN-2
CAS: 1042780-52-8 F: C14H10N2O2 W: 238.24
PARP10-IN-2 is a potent mono‐ADP‐ribosyltransferase PARP10 inhibitor with an IC50 of 3.64 μM for human PARP10. PARP10
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