| Bioactivity | PARP1-IN-20 (compound 19A10) is a potent inhibitor of PARP1, with the IC50 of 4.62 nM and has similar low PARP-Trapping effect compared with Veliparib(HY-10129, IC50 (MDA-MB-436) >100 μM)[1]. |
| CAS | 2659357-95-4 |
| Formula | C23H19BrN6O3S |
| Molar Mass | 539.40 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Xiaoyu Peng, et al. High affinity and low PARP-trapping benzimidazole derivatives as a potential warhead for PARP1 degraders. Eur J Med Chem. 2024 May 5:271:116405. |
PARP1-IN-20
CAS: 2659357-95-4 F: C23H19BrN6O3S W: 539.40
PARP1-IN-20 (compound 19A10) is a potent inhibitor of PARP1, with the IC50 of 4.62 nM and has similar low PARP-Trapping
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.